Brain normothermia therapy
for brain injured patients
TEQCool’s intended therapy is dedicated to achieving and maintaining normothermia in the patient’s brain. The primary objective of the treatment is to prevent and manage neurologic fever in brain injured patients. The system will support healthcare professionals to achieve stable normothermia by continuous brain temperature monitoring.
The cooling is transferred to the patient via balloon catheters in the nasal cavities. The physiological proximity of the nasal cavity to the brain results in short response time and more precise brain temperature control.
Healthcare professionals can also freely access the full patient body throughout the cooling treatment which minimize impact on the patient care. The system does not require any surgerical procedures and is minimally invasive.
TEQCools normothermia system consists of a cooling device and two separate single-use nasal cooling kits. The device has two cooling elements and two pumps to which the cooling kits are connected. The treatment is controlled and monitored via a large and adjustable touch screen.
The single-use nasal cooling kit consists of a tubing set with a heat exchanger bag that is inserted into the cooling elements on the device. The nasal balloon catheter is inserted to the patient’s nasal cavity and connected to the tubing set. Thereby a closed system is created, in which the cooled saline solution is circulated.
The embedded software automatically regulate the cooling power based on the patient’s brain temperature. The system requires both a brain temperature source to measure, monitor, display and regulate brain temperature, and a body temperature source for optimization and safety purposes.
TEQCool’s novel brain normothermia treatment will offer several unique benefits. Rapid selective brain cooling combined with precise brain temperature control are the most important therapeutic benefits, with the potential to significantly improve the cooling treatment of brain injured patients.
Rapid brain cooling
The rapid internal brain cooling, via the nasal cavities, has the capacity to reduce the brain temperature approximately 2ºC in ≤ 1 hour in a controlled manner. The treatment is safe and tolerable and does not require any surgery. The body temperature will gradually converge towards the brain temperature over a number of hours. The total cooling power transferred to the patient is significantly lower than with conventional cooling systems.
Brain temperature control
The system will monitor, control and display the brain temperature.