Brain normothermia therapy
for brain-injured patients

TEQCool’s intended therapy is dedicated to achieving and maintaining normothermia in the patients brain. The primary objective of the treatment is to prevent and manage neurogenic fever in braininjured patients. The system will support healthcare professionals to achieve stable normothermia by continuous regulation of brain temperature.


The cooling is transferred to the patient via balloon catheters placed in the nasal cavity. The physiological proximity of the nasal cavity to the brain results in short response time and more precise brain temperature control.


Healthcare professionals can thereby freely access the patient body throughout the cooling treatment which minimizes impact on the patient care. The treatment does not require any surgical procedures and is minimally invasive.

Treatment system

TEQCool’s normothermia system consists of a cooling device and two separate single-use nasal cooling kits. The device has two cooling elements and two pumps to which the cooling kits are connected. The treatment is controlled and monitored via an adjustable touch screen.

The single-use nasal cooling kit consists of a tubing set with a heat exchanger bag that is inserted into the cooling elements on the device. The nasal balloon catheter is inserted into the patient’s nasal cavity and connected to the tubing set. Thereby a closed system is created, in which the cooled saline solution is circulated.


TEQCool’s novel brain normothermia treatment will offer several unique benefits. Rapid selective brain cooling combined with precise brain temperature control are the most important therapeutic benefits, with the potential to significantly improve the cooling treatment of brain-injured patients.


Rapid brain cooling
The rapid internal brain cooling, via the nasal cavity, has the capacity to reduce the brain temperature approximately 2ºC in one hour1. The treatment is safe and tolerable and does not require any surgery. The total cooling power transferred to the patient is significantly lower than with conventional cooling systems.