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MEDICAL USE

TEQCool has one mission: to protect the brain when every second counts.

Our innovative brain cooling therapy is intended for use in critically brain-injured patients with persistent, hard-to-treat fever, especially in neuro-intensive care settings where swift, targeted action can be life-saving.

Why Brain Cooling in Neurological Care​

The brain is highly sensitive to temperature, and even mild fever or elevated temperature​ can exacerbate injury. ​ Targeted brain cooling helps by:

  • Reducing metabolic and oxygen demand, easing the burden on injured tissue, preventing cerebral swelling and oxidative stress.
  • Minimizing neurotoxic chemical buildup like glutamate, potassium, and calcium accumulation which contributes to cellular damage after hypoxia (oxygen deprivation) or elevated temperature..
  • Supporting neurological recovery, improving survival and long-term outcomes.

TEQCool’s targeted approach addresses these needs with speed, precision, and safety, marking a significant advancement in neuroprotective care.

Potential Clinical Applications in Neurocritical Care​ ​

TEQCool’s targeted brain cooling technology has the potential to reduce brain temperature by approximately 2ºC within one hour. This rapid, focused cooling is both safe and well tolerated, without the need for surgical procedures. Its efficiency stems from the proximity of the nasal cavity to the brain, requiring far less cooling power than conventional systems—making it ideal for time-critical interventions.

Click to read more about potential Neurological applications

Traumatic brain injury

TBI occurs when a blow or jolt to the head causes brain dysfunction, swelling, and pressure buildup which increases intracranial pressure and disrupts brain metabolism, leading to further damage. TEQCool’s Targeted Brain Cooling has the potential to help stabilize brain metabolism and reduce inflammation, creating a safer window for recovery.

Subarachnoid Hemorrhage (SAH)

SAH is bleeding in the space between the brain and its surrounding membrane, often caused by a ruptured aneurysm. It can lead to dangerous complications like vasospasm and delayed brain ischemia. TEQCool’s Targeted Brain Cooling has the potential to enable precise fever control and may reduce temperature-driven metabolic stress—protecting brain function when perfusion is compromised.

Status Epilepticus (SE)

SE is a prolonged or repeated seizure that doesn’t respond well to medication. It places extreme metabolic demand on the brain and can lead to irreversible damage. TEQCool’s Targeted Brain Cooling therapy has the potential to calm neuronal hyperactivity and limit further neurological damage.

Acute Encephalopathy

This is a broad term for brain dysfunction often caused by infection, toxins, or metabolic imbalance. It can lead to fever, inflammation, and widespread neural stress.TEQCool’s Targeted Brain Cooling has the potential to help mitigate neuroinflammation and support better cognitive recovery.

Ischemic Stroke and Brain Ischemia

This is caused by a blockage in a blood vessel, cutting off oxygen and nutrients to parts of the brain. Brain cells begin to die within minutes, and surrounding tissue is at risk.Reduced blood flow deprives brain cells of oxygen, accelerating cell death. Cooling the brain with TEQCool’s Targeted Brain Cooling therapy has the potential to help slow damage progression and protect surrounding tissue during acute care.

Neonatal Hypoxic-Ischemic Encephalopathy (HIE)

This is a type of brain injury in newborns due to oxygen deprivation during or around birth. It can cause long-term developmental delays or disability. TEQCool’s Targeted Brain Cooling has the potential to support gentle, precise, and controlled brain cooling tailored to each infant’s condition —improving chances for survival and neurodevelopment.

Cardiac Arrest

This is a sudden stop of the heart, cutting off oxygen to the brain and body. Even if the heart is restarted, the brain remains at risk from secondary ischemic damage in Post-cardiac arrest patients. TEQCool’s Targeted Brain Cooling therapy has the potential to provide precise temperature control to help optimize brain recovery in this high-risk group.

Migraine

A complex neurological disorder involving severe headaches, often linked to abnormal brain signaling and inflammation. Chronic or severe migraines can be disabling and resistant to treatment TEQCool’s Targeted Brain Cooling therapy has the potential to help calm overactive neural pathways and ease pain.